Repeated implantation failure versus repeated implantation success: discrimination at a metabolomic level
نویسندگان
چکیده
منابع مشابه
Repeated Implantation Failure
Successful embryo implantation is a process which requires both a synchronous development and interaction between hatched blastocyst and endometrium. The process of implantation as a scheme is presented in Pic. 1, where the diagram shows a preimplantation stage of embryo and some important factors thought to be necessary for uterine receptivity: COX-2 (cyclooxygenase-2), EGF (epidermal growth f...
متن کاملCytokine Profile in the Endometrium of Normal Fertile and Women with Repeated Implantation Failure
Background: Repeated Implantation Failure (RIF) is one of the most intricate obstacles in assisted reproduction. The cytokine and chemokine composition of uterine cavity seem to play important roles in the implantation process. Objective: To compare the cytokine profile in the endometrium of normal fertile women and those with repeated implantation failure. Methods: After enzymatic digestion of...
متن کاملP-214: Parental Contribution of HLA-G*0106 and G*0105N to Repeated Implantation Failure
Background: HLA-G, as a tolerogenic molecule, expressed in cytotrophoblast cells and playing an important role in the suppression of the immune response in maternal decidua. Today Interaction of the extracellular domains of HLA-G protein with cell receptors of immune system, including CD8, LILRB1, LILRB2 and killer cell immunoglobulin-like receptor KIR2DL4, was well known. Materials and Methods...
متن کاملsurrogacy as a good option for treatment of repeated implantation failure: a case series
background: repeated implantation failure (rif) is defined as pregnancy failure after two to six times with at least ten high grade embryo transfer to uterus. a variety of causes have been anticipated for rif, including anatomical, autoimmune, genetics, endocrine and thrombotic anomalies. factors responsible for rif have important implication regarding treatment however in many couples a perfec...
متن کاملThe role of oxytocin antagonists in repeated implantation failure
A prospective cohort study has been performed to find out if the administration of an oxytocin antagonist (Atosiban) at the occasion of embryo transfer has an effect on the pregnancy rate in patients with repeated failure of implantation. A total of 52 women with repeated failure of implantation after IVF/ICSI were included in this study. The ongoing pregnancy rate (OPR) in the total group of p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Human Reproduction
سال: 2016
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/dew064